aluminium phosphide side effects
November 13th, 2020

* Breathing Aluminum Phosphide can irritate the nose, throat and lungs causing coughing, wheezing and/or shortness of breath. Never delay or disregard seeking professional medical advice from your doctor or other qualified health care provider because of something you have read on WebMD. Phosphide poisoning: a review of literature. Eating aluminium phosphide can cause pain in the throat and stomach, nausea, vomiting and laboured breathing. Don’t include personal or financial information like your National Insurance number or credit card details. %%EOF All content is available under the Open Government Licence v3.0, except where otherwise stated, If you use assistive technology (such as a screen reader) and need a This file may not be suitable for users of assistive technology. Supportive measures are all that can be offered and should be implemented as required. Health Hazard Information Acute Health Effects The following acute (short-term) health effects may occur immediately or shortly after exposure to Aluminum Phosphate: f Contact can irritate and burn the skin and eyes. 2019 Nov 17;7(1):e69. Aluminium phosphide is a highly toxic inorganic compound with the chemical formula Al P used as a wide band gap semiconductor and a fumigant. 0 Aluminum phosphide is a well-known insecticide that has been banned in several countries due to its high fatality rate. 0000002357 00000 n %PDF-1.6 %���� 0000007908 00000 n �o�k���zQc!����~-M��m,C��mel���Vl �9�%������ ~�����_.�qM(71I��*��� :,h��Q��l��a���ƪ�e���*�p?j�����Zr��ggN��M�$�0�|,sb���T���h�� k�PY�LŹ5��$8ʇ:���Ռ‚7�qG�j�� ɿ Increased utilization of AlP for agricultural and non-agricultural purposes during the last four decades has resulted in increment of AlP-attributed poisoning numbers. Acute liver failure secondary to yellow phosphorus rodenticide poisoning: Outcomes at a center with dedicated liver intensive care and transplant unit. HHS Metabolic acidosis, or mixed metabolic acidosis and respiratory alkalosis, and acute renal failure are frequent. J Appl Toxicol. Aluminum phosphide poisoning: an unsolved riddle. [10][9], Aluminium phosphide has a fatal dose of between 0.15 and 0.5 grams (0.0053 and 0.0176 oz). Ref: PHE publications gateway number: 2014790 This colorless solid is generally sold as a grey-green-yellow powder due to the presence of impurities arising from hydrolysis and oxidation Properties. However, it is still used in certain countries to help protect stored grains from pets and rodents. We’ll send you a link to a feedback form. eCollection 2019. 0000003558 00000 n * Contact can irritate the skin and eyes. Successful management of zinc phosphide poisoning-a Hungarian case. 24 35 Click here to redeem . 0000061638 00000 n How Long Does Coronavirus Live On Surfaces? 0000001431 00000 n Fox JH, Porter BF, Easterwood L, Hildenbrand JRV, Hélie P, Smylie J, O'Toole D. J Vet Diagn Invest. Aluminium phosphide: health effects and incident management Information on aluminium phosphide, for use in responding to chemical incidents. 0000009179 00000 n Correction of metabolic acidosis is a cornerstone of treatment. [21] Several incidents of death in travelers in Thailand and other parts of Southeast Asia may have been caused by aluminum phosphide or chlorpyrifos, an organophosphate insecticide, used in an attempt to kill bedbugs in hotels. Smart Grocery Shopping When You Have Diabetes, Surprising Things You Didn't Know About Dogs and Cats, Coronavirus in Context: Interviews With Experts. Management: Sign Up to Receive Our Free Coroanvirus Newsletter, IMPORTANT information about user generated content. Below is a list of common natural remedies used to treat or reduce the symptoms of Aluminum-Phosphide-Poisoning. <]>> Signs and Symptoms of Acute Aluminum Phosphide Exposure: Acute exposure to aluminum phosphide usually results in headache, cough, tightness and pain in the chest, shortness of breath, dizziness, lethargy, and stupor. Mitochondrial electron transport chain complexes, catalase and markers of oxidative stress in platelets of patients with severe aluminum phosphide poisoning. ", "Acute aluminium phosphide poisoning: an update", "Aluminum Phosphide Poisoning-Related Deaths in Tehran, Iran, 2006 to 2013", "4 children killed after pesticide released toxic gas underneath their home, police say", "Pesticide in Alberta deaths may have killed Quebec sisters in Thailand in 2012", "Potent bed bug poison may have killed Canadian tourist, friend in Vietnam", "PHOSPHINE GAS POISONING - FRANCE: FATAL", "4 crew poisoned by fumigation, 1 died, France", "Aluminum phosphide poisoning in Saudi Arabia over a nine-year period",, Poisoning and certain other consequences of external causes, Creative Commons Attribution-ShareAlike License, This page was last edited on 11 October 2020, at 22:58. 0000065159 00000 n 0000003046 00000 n Sodium Aluminum Phosphate (SALP) E541 is a leavening agent. 0000001015 00000 n [1][2], After ingestion, toxic features usually develop within a few minutes. After ingestion, toxic features usually develop within a few minutes. NIH Metabolic acidosis, or mixed metabolic acidosis and respiratory alkalosis, and acute renal failure are frequent. This information may not fit your specific health circumstances. 2019 Dec;23(Suppl 4):S272-S277. [10] Since 1992, when aluminium phosphide became freely available in the market, it had, reportedly, overtaken all other forms of deliberate poisoning, such as organophosphorus and barbiturate poisoning, in North India. 0000005774 00000 n 0000008426 00000 n Other features include disseminated intravascular coagulation, hepatic necrosis and renal failure. Online ahead of print. The major lethal consequence of aluminium phosphide ingestion is profound circulatory collapse, and is reportedly secondary to these toxins generated, which lead due to direct effects on cardiomyocytes,[3] fluid loss, and adrenal gland damage. Clinical features: Get the latest research from NIH: We use cookies to collect information about how you use GOV.UK. [4] The signs and symptoms are non-specific, dose dependent and evolve with time passing. 2009 Sep;47(8):838-9; author reply 839. doi: 10.1080/15563650903203684. The major lethal consequence of phosphide ingestion, profound circulatory collapse, is secondary to factors including direct effects on cardiac myocytes, fluid loss, and adrenal gland damage. 0000008664 00000 n There is no antidote to phosphine or metal phosphide poisoning and many patients die despite intensive care. 0000003099 00000 n 2011 Aug;31(6):499-505. doi: 10.1002/jat.1692. Get a month of TabletWise Pro for free! In addition, phosphine and phosphides have corrosive actions. [18][19] Deaths have also been reported in Iran. Teach 0000002516 00000 n You’ve accepted all cookies. This failure of cellular respiration is likely to be due to a mechanism other than inhibition of cytochrome C oxidase. In addition, phosphine and hydrogen peroxide can interact to form the highly reactive hydroxyl radical and phosphine also inhibits catalase and peroxidase; both mechanisms result in hydroxyl radical associated damage such as lipid peroxidation. 0000002763 00000 n 0000006607 00000 n version of this document in a more accessible format, please email [22][23] In February 2020, aluminum phosphide poisoning resulted in one death and three serious injuries aboard a cargo ship traveling near France,[24] as the result of a botched fumigation procedure. COVID-19 is an emerging, rapidly evolving situation. To help us improve GOV.UK, we’d like to know more about your visit today. Acute poisoning with these compounds may be direct due to ingestion of the salts or indirect from accidental inhalation of phosphine generated during their approved use. You can change your cookie settings at any time. Aluminum phosphide intoxication mimicking ischemic heart disease led to unjustified treatment with streptokinase.

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